\documentclass[tikz]{standalone}
%\usepackage{tikz}
\begin{document}
\begin{tikzpicture}[circuit ee IEC, set resistor graphic=var resistor IEC graphic] 
  \pgfmathsetmacro{\shift}{4}


\foreach \contact/\y in {1/\shift,2/1.5*\shift,3/2*\shift}
{
\node [contact] (down contact \contact) at (\y,0) {};
\node [contact] (up contact \contact) at (\y,\shift) {};
}

\node [contact] (down contact 4) at (0,0) {};
\node [contact] (down contact 5) at (-\shift,0) {};
\node [contact] (ground contact) at (1.5*\shift+3,\shift) {};

\node (e_text) at (1.5*\shift,\shift+1.5){Extracellular};
\node (e_text) at (1.5*\shift,-1.5){Intracellular};

\node (e)[circle, draw, fill=white, inner sep = 2pt] at (1.5*\shift,-1) {};
\draw {(down contact 2)-- (e)};

\node (i)[circle, draw, fill=white, inner sep = 2pt] at (1.5*\shift,\shift+1) {};
\draw {(up contact 2)-- (i)};

%V
\node (v) at (3*\shift+2, 0.5*\shift) {$V_3$};
\draw [triangle 45-]{(3*\shift+2,-1) -- ++(up:0.5+0.5*\shift)};
\draw [triangle 45-]{(3*\shift+2,\shift+1) -- ++(down:0.5+0.5*\shift)};

%circuit
 %clockwise Em
\draw (down contact 1) -- (down contact 4)
                       to [capacitor={info={$C_{m_3}$}}] ++(up:\shift)
                       -- (up contact 1)
                       to [ resistor = {info' = {$R_{m_3}$}, near start},
                       battery={info'={$E_{m_3}$}, near end}] (down contact 1);
                     
%counterclockwise Ek
\draw (down contact 1) -- (down contact 3)
                       to [battery={info'={$E_{K_{Ca}}$}, rotate={180},near start},
                       resistor = {info = {$g_{K_{Ca}}$}, adjustable', near end}] (up contact 3)
                       -- (up contact 1);
%counterclockwise ENa
\draw (down contact 3) -- ++(right:\shift)
                       to [  battery={info={$E_{Ca}$}, near start},
                       resistor = {info = {$g_{Ca}$}, adjustable', near end}] ++(up:\shift) 
                       -- (up contact 3);


%ground
\draw (ground contact) -- ++(up:1) -- ++ (right:1)
to [ground={pos=1}] ++(down:0.5);
%\end{scope}

%Ra
\draw (down contact 4) to [resistor={info={$Ra_3/2$}}](down contact 5);


\end{tikzpicture}
\end{document}